ppat.1011366.s002.docx (197.92 kB)
Viral load detected by qRT-PCR in col-51 and N2 worms during Orsay infection.
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posted on 2024-01-08, 18:31 authored by Ying Zhou, Hanqiao Chen, Weiwei Zhong, Yizhi Jane TaoViral load detected by qRT-PCR in col-51 and N2 worms during Orsay infection.
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ubiquitin protein modificationsthree new pathwaysmediated rna interferenceintracellular pathogen responseinhibit viral infectionhost interaction networksdestabilizes viral rnasconvoluted apical bordernovel antiviral pathwaysmount antiviral responsessmall animal modelintestinal actin (<chromatin remodelers (<wide rnai screensanother physical barrierorsay virus identifiedcollagens likely formphysical barrieractin remodelersorsay virusantiviral activitieslikely functionintact animaldissecting virusworm intestinewidely usedvisible changesterminal webresults indicateprevious studiesperformed genomemutant wormsliving nematodeintestine cellsinfected cellsevidence suggestsepigenetic regulatorsentire genomeelegans disease mechanismscritical componentcomprehensively searchalso holds5 34
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