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Two new metabolites from Daldinia eschscholtzii, an endophytic fungus derived from Pogostemon cablin

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posted on 2017-10-24, 10:52 authored by Hong-Xin Liu, Hai-Bo Tan, Sai-Ni Li, Yu-Chan Chen, Hao-Hua Li, Wei-Min Zhang

The chemical investigation of the mycelia of endophytic fungus Daldinia eschscholtzii A630, which was isolated from the medicinal plant Pogostemon cablin, resulted in the isolation of two new compounds, named eschscholin A (1), 3-ene-2-methyl-2H-1-benzopyran-5-ol (2), and one new natural product 3,5-dihydroxy-2-methyl-4H-chromen-4-one (3), along with seven known compounds. Their structures were fully characterized by means of detailed spectroscopic analysis, and in comparison with published data for known compounds. All of the isolated compounds (110) were evaluated for their antibacterial activities.

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