posted on 2024-03-05, 19:44authored byNaohiro Kashimura, Yuki Suzuki, Takayuki Nonoyama, Jian Ping Gong
Learning
from nature is a promising approach to achieving specific
functions of synthetic materials. The high material functions, in
turn, shed light on the fundamental mechanisms underlying the high
performance of biological tissues. For instance, bone is an attractive
metabolic tissue with fascinating capabilities from the perspective
of both biochemical and biomechanical functionalities. Bone tissue
exhibits exceptional mechanical performance as a skeleton, enabling
to sustain the locomotion of mammals. In this study, we design coupled
reactions for self-regulatory sacrificial bond formation in poly(acrylic
acid) hydrogels by introducing biomineral hydroxyapatite (HAp) found
in bones. We demonstrate that through five coupled reactions, HAp
regulates the Ca2+ bridging to the acidic polymer and toughens
the hydrogels in water by the sacrificial bonds effect. This work
is expected not only to greatly contribute to the design of tough
soft materials but also to give deep insights into the self-regulated
bone-toughening mechanisms.