pone.0278392.s001.docx (24.79 kB)
Top 60 genes associated with grip strength-depression from gene-based analysis.
journal contribution
posted on 2022-12-15, 18:34 authored by Tianhao Zhang, Lujun Ji, Jia Luo, Weijing Wang, Xiaocao Tian, Haiping Duan, Chunsheng Xu, Dongfeng Zhang(DOCX)
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wide association studysup > 8722suggestive significance (<significant inverse associationseveral studies foundexplore potential snps7 snps exceeded336 snps reachedcalculate genetic correlations15 top snpsdiv >< pgenetic correlation coefficientused twin datacommon physiological mechanisms41 (- 0pleiotropy analysis showspathway enrichment analysisdepression pgenetic correlationpleiotropy analysisresulting snpsp 15 ).eqtl analysisbased analysisskeletal musclepsychiatric disorderpascal softwarenervous systemmuscle strengthmainly enrichedgrip strengthdizygotic twinsbivariate gwasalso evidence139 pairs
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