pone.0296737.s002.docx (33.14 kB)
The names and immunogenicity values of 177 therapeutic antibody samples in the training dataset.
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posted on 2024-02-23, 18:42 authored by Hong Wang, Xiaohu Hao, Yuzhuo He, Long FanThe names and immunogenicity values of 177 therapeutic antibody samples in the training dataset.
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principal component analysiscorresponding web serverremaining 22 samplesfirst calculated usingtest results showindependent test datasetweighted ensemble modelantibody variable regiondiv >< pproposed method outperformsbased sequence featuresimmunogenicity prediction methodantibody therapeutics developmentbased featuresantibody therapeuticsantibody sequenceusing wetprediction methodscomputational methodcomparison method177 samplesfinal featurestrained modelmodel trainingconstructed modeltwo dimensionstherapeutic antibodiesofficial websitelab experimentsimportant factorimmunogenicity great significancefold crossextracted featureearly stagedevelopment processcollected dataclinical applicationscertain extentbest oneamino sequences7273 accuracy
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