ppat.1011791.s002.docx (31.05 kB)
Table showing gene categories, protein, and gene symbols, analyzed proteins/genes, gene name, function, and their upregulation and downregulation in condition: uninfected, EM infected and IOE infected.
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posted on 2023-11-13, 18:39 authored by Aditya Kumar Sharma, Abdeljabar El Andaloussi, Nahed IsmailTable showing gene categories, protein, and gene symbols, analyzed proteins/genes, gene name, function, and their upregulation and downregulation in condition: uninfected, EM infected and IOE infected.
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restored cell viabilityreactive oxygen speciesenhanced bacterial clearanceemploying murine modeldownstream target gpx4attenuated liver pathologyacute liver damageoxidative signaling pathwayfatal toxic shockcauses excessive inflammationattenuated oxidative stressinduces nrf2 activationcaspase 11 activationcaspase 11liver tissueliver injurynrf2 activationdeleterious activationtargeting antiprolonged survivalpreviously showednrf2 signalingnrf2 expressionmay progressmammalian cellskey stepkey approachjaponica inflammasome pathwaysinfected micefirst timefatal ehrlichiosisendoplasmic reticulumehrlichia e developed mechanismsdecreased inflammationd3t resultedd3t ),antioxidant 3h
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