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Systematic review to estimate failure rates of ACTs in sub-populations of interest.
journal contribution
posted on 2023-12-01, 18:24 authored by Abena Takyi, Verena I. Carrara, Prabin Dahal, Marianna Przybylska, Eli Harriss, Genevieve Insaidoo, Karen I. Barnes, Philippe J. Guerin, Kasia StepniewskaSystematic review to estimate failure rates of ACTs in sub-populations of interest.
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new antimalarials developmentcurrent antimalarials maybaseline act efficacybased combination therapybased combination therapiesanalyses using fixedantimalarial drug resistanceuncomplicated cases ).div >< plargest risk groupstreatment failures rangeduncomplicated malaria casesestimated nearly 11 million uncomplicatedafrica treatment failuresp antimalarial dosinguncomplicated confirmedtreatment durationfalciparum 352 million338 million3 million2 millionstudy showsstudy aimsserious threatsaharan africarisk grouppublished metapregnant womenpopulation structurepeople livingoverweight adultsoptimally dosedoptimal dosingmalaria controllevel dataexcess numberestimated 153elimination effortseffect metaconfirmed recrudescence5 years4 people
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