pbio.3001468.s012.pdf (125.18 kB)
Supporting information methods, notes on experimental results, and Supporting information tables.
journal contribution
posted on 2021-12-03, 18:40 authored by Gabriel Piedrafita, Sreejith J. Varma, Cecilia Castro, Christoph B. Messner, Lukasz Szyrwiel, Julian L. Griffin, Markus RalserDetails of materials and reagents used and the cysteine quantitation procedure are described as Supporting information methods, followed by notes discussing pH-dependent product formation and the role of cysteine functional groups, and Supporting information tables with additional data on trace Fe quantitation and 1H-NMR T1 measurements across proton peaks in different setups.
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provided experimental supportchicken &# 8211proteinogenic amino acidspentose phosphate pathwaymetabolism typical temperaturedriven reaction networkcould evolution kicknonenzymatic reaction sequencesamino acidsmetabolic networkearly evolution&# 8220xlink ">vitro screeningstepwise enzymatizationsimplest componentsremain conservedrecent discoveryproviding insightsprebiotically availableppp ).phosphate formsparticular attentionoxidative pppnonenzymatic reactionslimiting stepleast partknow littlehighly conservedhigh specificityevolutionary originsenvironmental conditionsegg dilemmaadditive effectsaccelerating effects
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