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Supporting information.

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posted on 2024-02-20, 18:20 authored by Luca Sesta, Andrea Pagnani, Jorge Fernandez-de-Cossio-Diaz, Guido Uguzzoni

Additional details about methods, datasets and further results.

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    PLOS Computational Biology

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    variants enrichment ratiosquantify protein activityprotein fitness landscapepossible protein variantsfitness landscape reconstructionsthroughput screening methodsdiv >< pseveral experimental casessequencing data derivedannealdca silico seq datapropose annealdcawithout relyingused eventherapeutic applicationstested usingspecific taskssmall fractionsequence spacescreening experimentsmolecular biologymajor challengelearning frameworkimportant diagnosticimmunized micegiven functionfittest moleculescomputational modelsbroad rangeantibody rep

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