pgen.1010540.s001.pdf (7.06 MB)
Supplementary figures, tables, and methodological details.
journal contribution
posted on 2022-12-12, 18:38 authored by Martin Jankowiak, Fritz H. Obermeyer, Jacob E. LemieuxThis supplementary pdf contains Figures A-TT and Tables A-F as well as detailed descriptions of our data processing pipeline, modeling assumptions, and inference approach.
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relative growth ratespivotal role playedpairwise interaction effectsallele frequency spacescalable probabilistic methodless well characterizedidentify numerous mutations9 million sarsinferring selection effectsdifferential viral fitnessselection actsviral lineagesviral evolutionxlink ">vaccination statusunprecedented viewspike proteinsequence millionsnucleocapsid proteinsn501 residuelasting vaccinesincrease fitnessidentifying fitnessglobal effortgenetic determinantsdiffusion approximationdeveloping effectivebvas ),baseline modelassociated mutationsapply bvasanalyses point
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