pone.0291947.s001.pdf (2.14 MB)
Supplementary figures and tables.
journal contribution
posted on 2024-02-09, 18:31 authored by Olga Li, Jason A. Hackney, David F. Choy, Diana Chang, Rhea Nersesian, Tracy L. Staton, Fang Cai, Shadi Toghi EshghiThis file contains the supplementary figures and tables referenced in this study.
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support personalized therapylower clinical benefitdownstream bioinformatics analysischronic spontaneous urticariaasthmatic patient subpopulations96 %, 96targeted amplicon nextdiv >< preported ngs assayfs supgeneration sequencing assaytryptase gene locitargeted nextgeneration sequencingtpsb2 tpsab1 sanger sequencingα duplicationwhole bloodtryptase locitryptase genotypingtryptase allelestherapeutic targetsevere asthmasequence identityprovides coverageperipheral tryptasemast cellmakes genotypinginactive αhigher levelshigh levelshealthy donorsgenotyping callsevaluate knowneffective methoddna extracteddetermining polymorphismschallenging taskasthma patientsassess response>, respectively
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