pone.0258316.s001.pdf (737.73 kB)
Supplementary experimental methods.
journal contribution
posted on 2021-10-21, 17:30 authored by Paul A. Wilson, Sara Santos Franco, Liu He, Nicholas W. Galwey, Jackie Meakin, Rebecca McIntyre, Simon M. McHugh, Michael A. Nolan, Sarah L. Spain, Thaddeus Carlson, Mercedes Lobera, Justin P. Rubio, Bill Davis, Linda C. McCarthy(PDF)
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type 3 immunitysup >+several autoimmune diseasesprofiles reported perturbationinflammatory bowel diseasedifferential detoxification responseconcept study indicatedcellular detoxification responseattractive therapeutic targetcell maintenance mediumcell differentiation eventswide association studiesmetabolic signalling networksmay perturb immunesignificant contributory rolediv >< prorc inverse agonistfour culture conditionsdriven transcriptional effectsassociated rorc variantibd risk associatedcells transcriptional effectssignificant associationcell lineagesmetabolic pathwaystranscriptomic effectssignificant effectrorc knockgenotype maysix dayspreferentially expressedobservation justifiesmean numberlarger cohortinactive diastereomergreatly diminishedderived rnacritical regulatorcontrol ).allele ).
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