figshare
Browse
pone.0293845.s006.docx (49.77 kB)

Summary of RT-QuIC endpoint dilution experiments.

Download (49.77 kB)
journal contribution
posted on 2023-11-02, 17:55 authored by Charlotte M. Thomas, M. Khalid F. Salamat, Christopher de Wolf, Sandra McCutcheon, A. Richard Alejo Blanco, Jean C. Manson, Nora Hunter, E. Fiona Houston

BH, brain homogenate; Proportion of positive replicates defined as: The number of replicate reactions that exceed threshold by cut-off time (50 h)/total number of replicates (n = 10) at a given BH dilution. a Log10 SD50 units (± standard error) present in 2 μg brain calculated according to Spearman-Kärber method, Eqs (1) & (2). b The number of SD50 units per g of brain.

(DOCX)

History

Usage metrics

    PLOS ONE

    Categories

    Keywords

    iron oxide beadsbovine spongiform encephalopathyscreen blood donationscontaminated blood wouldwhole blood samplessheep experimentally infectedsc misfolded prion proteineither assay maydiv >< phuman blood samplessensitive diagnostic testblood samplesinfected sheepscreening testprevent humanhuman transmissionvariant creutzfeldtupon additiontwo yearstime quakingsensitive realroutinely usedresults supportprion infectionjakob diseaseintracerebral inoculationinduced conversionextremely raredisease onsetcapture step

    Licence

    CC BY 4.0

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC