posted on 2021-05-14, 18:36authored byZhiyi Yuan, Yunke Zhou, Zhen Qiao, Chan Eng Aik, Wei-Chen Tu, Xiaoqin Wu, Yu-Cheng Chen
Chiral
light–matter interactions have emerged as a promising
area in biophysics and quantum optics. Great progress in enhancing
chiral light–matter interactions have been investigated through
passive resonators or spontaneous emission. Nevertheless, the interaction
between chiral biomolecules and stimulated emission remains unexplored.
Here we introduce the concept of a biological chiral laser by amplifying
chiral light–matter interactions in an active resonator through
stimulated emission process. Green fluorescent proteins or chiral
biomolecules encapsulated in Fabry–Perot microcavity served
as the gain material while excited by either left-handed or right-handed
circularly polarized pump laser. Owing to the nonlinear pump energy
dependence of stimulated emission, significant enhancement of chiral
light–matter interactions was demonstrated. Detailed experiments
and theory revealed that a lasing dissymmetry factor is determined
by molecular absorption dissymmetry factor at its excitation wavelength.
Finally, chirality transfer was investigated under a stimulated emission
process through resonance energy transfer. Our findings elucidate
the mechanism of stimulated chiral light–matter interactions,
providing better understanding of light–matter interaction
in biophysics, chiral sensing, and quantum biophotonics.