ppat.1009465.s015.pdf (2.46 MB)
Spectral quantification of host proteins from exosomes from infected macrophages (48 hpi) in comparison to exosomes from uninfected macrophages.
journal contribution
posted on 2021-05-06, 17:26 authored by Winnie W. Hui, Lisa E. Emerson, Beata Clapp, Austin E. Sheppe, Jatin Sharma, Johanna del Castillo, Mark Ou, Gustavo H. B. Maegawa, Carol Hoffman, Joseph Larkin, III, David W. Pascual, Mariola J. FerraroCalculated fold change was based on the normalized spectral values, and p-values were calculated by using Fisher’s test. ID, Symbol, Entrez Gene Name as well as predicted protein type and targeting drugs have been shown (Ingenuity Pathway Analysis, IPA, Qiagen).
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clinically approved vaccine>- infected macrophagesmediated defense mechanismsbased network analysisinitiate mucosal immunity>- infected antigenvehicles transmitting antigensmucosal immune responseidentify host moleculesth1 cell biasantigen administration knowncells secreting th1derived small evsmediated immunityspecific cellsmall evsanalysis predictedtype immunityspecific th1induce th1exosomes derivedtype cytokinestrafficked viastudy helpssalmonella results demonstratepromote activationoverlooked aspectompa antibodiesnontyphoidal salmonellosisnegative bacteriamurine studiesmice administeredintracellular pathogenigg antibodieshelper 1future approachesevs ),delivered intranasallycomprehensive proteomecausative agentc miceanimals stimulated
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