ol6b01783_si_002.pdf (471.16 kB)
Silanediol-Catalyzed Chromenone Functionalization
journal contribution
posted on 2016-07-22, 20:50 authored by Andrea
M. Hardman-Baldwin, Michael D. Visco, Joshua M. Wieting, Charlotte Stern, Shin-ichi Kondo, Anita E. MattsonPromising
levels of enantiocontrol are observed in the silanediol-catalyzed
addition of silyl ketene acetals to benzopyrylium triflates. This
rare example of enantioselective, intermolecular chromenone functionalization
with carbonyl-containing nucleophiles has potential applications in
the synthesis of bioactive chromanones and tetrahydroxanthones.
