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Fig A. Flowchart showing the selection of studies. Fig B. Viral load detected in plasma in Mayaro infected cases per day post symptoms onset. Mean and range for 21 patients are shown. Fig C. Maximum likelihood EIP probability density function (left) and cumulative distribution function (right). The aggregated proportion of mosquitoes that tested positive at the relative days post-infection are shown as bars. Table A. Boolean algorithms for literature search. Table B. Data classification of MAYV studies in humans. Table C. Values used in estimate_R() function in EpiEstim package. Table D. Characteristics of Mayaro fever case reports. Table E. Characteristics of Mayaro fever cases included in the intrinsic incubation period analysis (N = 15). Table F. Characteristics of hospital-based surveillance studies included in the analysis. Table G. Characteristics of MAYV cross-sectional seroprevalence studies. Table H. Studies with possible evidence of MAYV transmission. These studies were not classified in other categories but strongly indicate presence of MAYV. Table I. Studies that detected MAYV in animals. Table J. Full genomes of MAYV included in the phylogenetic analysis. Table K. Nucleotide substitution models. The best-fitting model is in bold.

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