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Regional association plots for the locus of the two top SNPs rs11844522 (A) and rs5798227 (B) in the predicted COVID-19 GWAS (p ≤ 1x10-6).

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posted on 2021-08-11, 17:31 authored by Irene V. van Blokland, Pauline Lanting, Anil P. S. Ori, Judith M. Vonk, Robert C. A. Warmerdam, Johanna C. Herkert, Floranne Boulogne, Annique Claringbould, Esteban A. Lopera-Maya, Meike Bartels, Jouke-Jan Hottenga, Andrea Ganna, Juha Karjalainen, Caroline Hayward, Chloe Fawns-Ritchie, Archie Campbell, David Porteous, Elizabeth T. Cirulli, Kelly M. Schiabor Barrett, Stephen Riffle, Alexandre Bolze, Simon White, Francisco Tanudjaja, Xueqing Wang, Jimmy M. Ramirez III, Yan Wei Lim, James T. Lu, Nicole L. Washington, Eco J. C. de Geus, Patrick Deelen, H. Marike Boezen, Lude H. Franke

In each of the two panels, the top SNP is indicated by a purple diamond. Other SNPs are colored according to their linkage disequilibrium with the top SNP (calculated with the European population from the 1000 Genomes Project (phase 3) as a reference panel). The genes located within the visualized regions are drawn at their respective locations, with an arrow indicating the transcribed strand. Positions correspond to genome assembly GRCh37.

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