posted on 2021-06-22, 12:04authored byRan Wei, Claire L. Dickson, Dušan Uhrín, Guy C. Lloyd-Jones
Quantitative NMR spectroscopy (qNMR)
is an essential tool in organic
chemistry, with applications including reaction monitoring, mechanistic
analysis, and purity determination. Establishing the correct acquisition
rate for consecutive qNMR scans requires knowledge of the longitudinal
relaxation time constants (T1) for all
of the nuclei being monitored. We report a simple method that is about
10-fold faster than the conventional inversion recovery technique
for the estimation of T1.