Quantile-quantile plots (Q-Q plots) of the four phenotypes: Hospitalized COVID-19 vs. population, COVID-19 vs. self-reported negative, COVID-19 vs. population and predicted COVID-19 from self-reported symptoms vs. predicted or self-reported non-COVID-19, wherein variants are confined to a selection of associated with several viral infection traits.

van Blokland, Irene V.; Lanting, Pauline; Ori, Anil P. S.; Vonk, Judith M.; Warmerdam, Robert C. A.; Herkert, Johanna C.; Boulogne, Floranne; Claringbould, Annique; Lopera-Maya, Esteban A.; Bartels, Meike; Hottenga, Jouke-Jan; Ganna, Andrea; Karjalainen, Juha; Hayward, Caroline; Fawns-Ritchie, Chloe; Campbell, Archie; Porteous, David; Cirulli, Elizabeth T.; Barrett, Kelly M. Schiabor; Riffle, Stephen; Bolze, Alexandre; White, Simon; Tanudjaja, Francisco; Wang, Xueqing; Ramirez, Jimmy M.; Lim, Yan Wei; Lu, James T.; Washington, Nicole L.; de Geus, Eco J. C.; Deelen, Patrick; Boezen, H. Marike; Franke, Lude H.

doi:10.1371/journal.pone.0255402.s003

pone.0255402.s003.pdf (277.31 kB)

Quantile-quantile plots (Q-Q plots) of the four phenotypes: Hospitalized COVID-19 vs. population, COVID-19 vs. self-reported negative, COVID-19 vs. population and predicted COVID-19 from self-reported symptoms vs. predicted or self-reported non-COVID-19, wherein variants are confined to a selection of associated with several viral infection traits.

journal contribution

posted on 2021-08-11, 17:31 authored by Irene V. van Blokland, Pauline Lanting, Anil P. S. Ori, Judith M. Vonk, Robert C. A. Warmerdam, Johanna C. Herkert, Floranne Boulogne, Annique Claringbould, Esteban A. Lopera-Maya, Meike Bartels, Jouke-Jan Hottenga, Andrea Ganna, Juha Karjalainen, Caroline Hayward, Chloe Fawns-Ritchie, Archie Campbell, David Porteous, Elizabeth T. Cirulli, Kelly M. Schiabor Barrett, Stephen Riffle, Alexandre Bolze, Simon White, Francisco Tanudjaja, Xueqing Wang, Jimmy M. Ramirez III, Yan Wei Lim, James T. Lu, Nicole L. Washington, Eco J. C. de Geus, Patrick Deelen, H. Marike Boezen, Lude H. Franke

For every COVID-19 GWAS, a genomic inflation factor (λ) with accompanying p-value is shown. Based on both these values and the Q-Q plots, there is no indication of an increased viral infection signal in one of the COVID-19 phenotypes.

(PDF)