pgen.1009952.s006.pdf (188.45 kB)
Proportions of the open state across different tissue types in the 15-core ChromHMM state model.
journal contribution
posted on 2022-01-20, 18:40 authored by Henry Sung-Ching Wong, Szu-Yi Tsai, Hou-Wei Chu, Min-Rou Lin, Gan-Hong Lin, Yu-Ting Tai, Chen-Yang Shen, Wei-Chiao ChangThe figure shows that the proportions of open state (chromHMM state <7) are similar across all tissues. The 127 epigenomes from the 15-core chromatin state model were sorted into 29 tissue categories.
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sup > 8722slightly lower heritabilityprovide new insights37 × 10wide association studymoderate genetic correlationyielding 13 genomediv >< pwhr ), usingfour adiposity traitswide significantwc ),genetic underpinningsadiposity traitsvarious diseasesrisk factorsralgapa1 pleiotropic effectspias1 p overall adipositynucleotide polymorphismsneural pathwaysmass indexloci pairsknown geneincreased dramaticallyincluding bodyhip ratiogabrg1 fto east asiancombined prevalenceassociated traitabdominal adiposity460 single15q23 ])000 subjects
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