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Posttraumatic stress disorder in people with dementia: study protocol

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posted on 2024-03-15, 11:40 authored by J. E. Ruisch, D. C. D. Havermans, E. M. J. Gielkens, M. Olff, M. A. M. J. Daamen, S. P. J. van Alphen, M. van Kordenoordt, J. M. G. A. Schols, K. R. J. Schruers, S. Sobczak

Background: Posttraumatic stress disorder (PTSD) is considered an independent risk factor for dementia. Despite the (clinical) evidence that PTSD is associated with neuropsychiatric symptoms in people with dementia, studies on its prevalence and clinical manifestation are limited, and their quality is affected by the lack of a structured method to diagnose PTSD in this population. The primary aim of the current study is to validate the ‘TRAuma and DEmentia’ interview as a diagnostic tool for PTSD in people with dementia and to test feasibility of EMDR treatment for people with PTSD and dementia.

Methods: This prospective multi-centre study is divided into two parts. In study A, 90 participants with dementia will be included to test the criterion validity, inter-rater reliability and feasibility of the ‘TRAuma and DEmentia’ interview. In study B, 29 participants with dementia and PTSD will receive eye movement desensitisation and reprocessing therapy by a trained psychologist, and 29 participants with dementia and PTSD will be placed on the waiting list control group.

Conclusion: This study aims to improve the diagnostic process of PTSD and to assess the effects of eye movement desensitisation and reprocessing treatment in people with dementia living in Dutch care facilities.

Trial registration: NL70479.068.20 / METC 20-063 / OSF registration: https://doi.org/10.17605/OSF.IO/AKW4F

This study protocol describes a two-part study on posttraumatic stress disorder in people with dementia in Dutch care facilities.

The primary aim of the study is to validate the ‘TRAuma and DEmentia’ interview as a diagnostic tool for posttraumatic stress disorder in people with dementia.

This study aims to test the feasibility of an evidence-based treatment for people with dementia and posttraumatic stress disorder in the form of eye movement desensitisation and reprocessing therapy.

This study protocol describes a two-part study on posttraumatic stress disorder in people with dementia in Dutch care facilities.

The primary aim of the study is to validate the ‘TRAuma and DEmentia’ interview as a diagnostic tool for posttraumatic stress disorder in people with dementia.

This study aims to test the feasibility of an evidence-based treatment for people with dementia and posttraumatic stress disorder in the form of eye movement desensitisation and reprocessing therapy.

Funding

This work is partially supported by EMDR-Europe under grant number 2019-04, Alzheimer Nederland under grant number WE.09-2021-02/u210099/MB/be, and Universiteitsfonds Limburg/SWOL under grant number CoBes20.050.

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