ppat.1010159.s025.docx (16.16 kB)
Pixel intensity-based and spatial (distance between center-mass) colocalization analysis between Lamp1 and LC3b in RV-C15-infected HAE.
journal contribution
posted on 2022-01-07, 18:27 authored by Talita B. Gagliardi, Monty E. Goldstein, Daniel Song, Kelsey M. Gray, Jae W. Jung, Maxinne A. Ignacio, Kimberly M. Stroka, Gregg A. Duncan, Margaret A. Scull(DOCX)
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triggers cytopathic effectstight junction proteinshuman airway epitheliumhpi ), correlatingdiv >< pdifferent time points12 hours postepithelial barrier integrityepithelial cell organizationc15 replication sitesc replication comparedc15 infection resultedrhinovirus c replicationhae attenuated rvdsrna colocalization implicatedrhinovirus cepithelial functionc15 replicationc15 infectionc receptorvivo vitro unique featuresstranded rnarv infectionsrelated rhinovirusesprogeny virionsprimary sitepreviously reportedmechanism usedmay contributelytic releaselikely correspondinginterferon genesincomplete autophagyhigh ratiogenetic depletionfindings identifyfacilitate nonendoplasmic reticulumelevated titerselevated stimulatorciliated cellscharacterized rvcell levelapical compartment
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