Photochemical Synthesis
of 1,4-Dicarbonyl Bifluorene
Compounds via Oxidative Radical Coupling Using TEMPO as the Oxygen
Atom Donor

Xu, Jincheng; Ding, Aishun; Zhang, Yanbin; Guo, Hao

doi:10.1021/acs.joc.0c02781.s001

jo0c02781_si_001.pdf (6.54 MB)

Photochemical Synthesis of 1,4-Dicarbonyl Bifluorene Compounds via Oxidative Radical Coupling Using TEMPO as the Oxygen Atom Donor

journal contribution

posted on 2021-01-29, 20:14 authored by Jincheng Xu, Aishun Ding, Yanbin Zhang, Hao Guo

A visible-light-induced metal-free synthesis of 1,4-dicarbonyl compounds from alkyne-containing aryl iodides via photochemical C–I bond cleavage, intramolecular cyclization, oxidation, and intermolecular radical coupling sequence is reported. TEMPO was employed as the oxygen atom donor in this transformation. This protocol provided a new strategy for the synthesis of 1,4-dicarbonyl bifluorene compounds.