Version 2 2024-01-03, 20:17Version 2 2024-01-03, 20:17
Version 1 2024-01-03, 15:11Version 1 2024-01-03, 15:11
journal contribution
posted on 2024-01-03, 20:17authored bySouvik Adak, Sarah E. Braley, M. Kevin Brown
The saturation of aromatic scaffolds is valuable for
the synthesis
of complex rings. Herein, we demonstrate a process for photochemical
dearomative reduction of quinolines. The process involves capture
of a quinoline excited state with γ-terpinene. Importantly,
the reaction is chemoselective as other easily reduced functionalities
such as halogens or alkenes do not undergo reduction. The mechanism
of the reaction has also been investigated. Finally, the generality
of the approach towards other substrates is demonstrated.