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Perivascular lymphocytic inflammation in endocrine, respiratory, alimentary, hepatobiliary and pancreatic, and genitourinary tissues in MAYV-infected rhesus macaques at 10 dpi.

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posted on 2023-11-20, 18:42 authored by Whitney C. Weber, Caralyn S. Labriola, Craig N. Kreklywich, Karina Ray, Nicole N. Haese, Takeshi F. Andoh, Michael Denton, Samuel Medica, Magdalene M. Streblow, Patricia P. Smith, Nobuyo Mizuno, Nina Frias, Miranda B. Fisher, Aaron M. Barber-Axthelm, Kimberly Chun, Samantha Uttke, Danika Whitcomb, Victor DeFilippis, Shauna Rakshe, Suzanne S. Fei, Michael K. Axthelm, Jeremy V. Smedley, Daniel N. Streblow

Presence and relative intensity (+ to +++) of lymphocytic inflammation within tissues were assessed using the following scale:—, absence of pathology within sections; +, one small aggregate of perivascular lymphocytes; ++, multiple blood vessels within one or two areas of the tissue with small to moderate numbers of perivascular lymphocytes; +++, perivascular lymphocytes affecting a majority of blood vessels in small to moderate numbers with or without infiltration of the surrounding tissue. *, Chronic hepatic degeneration and regeneration; **, Rare attenuated cortical tubules, scant cellular or proteinaceous casts with few associated lymphocytes; and ***, diffuse chronic mild lymphocytic and neutrophilic urethritis.

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