pone.0299353.s001.docx (20.36 kB)
Patients’ clinical, epidemiological and histopathological data.
journal contribution
posted on 2024-02-29, 18:39 authored by Rafaela V. N. Silva, Lucas A. Berzotti, Marcella G. Laia, Liliane S. Araújo, Crislaine A. Silva, Karen B. Ribeiro, Millena Brandão, Adilha M. R. Michelleti, Juliana R. Machado, Régia C. P. LiraPatients’ clinical, epidemiological and histopathological data.
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revealing marked variationsrenal cell carcinomamethylenetetrahydrofolate dehydrogenase 2assessed using kmhigher fuhrman gradesgene expression comparisonsalthough prognostic valuelower survival ratesshorter overall survivallower expressions comparedtumors exhibited higherdiv >< pmthfd2 protein patternhigher mthfd2 tendedprotein profile needsnn samples respectivelymthfd2 protein expressionrcc histological subtypesdifferent rcc cohortsassess tumor prognosistumor samplesmthfd2 expressionlower intensityfree survivalshowing higherprotein levelsprotein immunostainingeven highershorter recurrencelarger tumorsgreater expressionexpression scoresprognostic indicatorprognostic factorsmthfd2 tumor subtypestumor characteristics117 rcctranscript levelsreliable biomarkerplotter toolpathological dataoften diagnosedmetastatic grouphistopathological diagnosiscommon typechrcc ).ccrcc comparedadvanced stages
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