Pairwise colocalization of GWAS signals with LINC-PINT and AC016831.7 cis-eQTLs at chr7q32.2.

(A) LocusCompare plot of chr7q32.2 locus variants’ -log₁₀(P) from BMI GWAS versus LINC-PINT cis-eQTL. Points are colored according to the variant’s r² with the reference variant, which is marked by the purple diamond. Posterior probability (PP) of a single, shared functional variant was calculated with HyPrColoc. (B) Same as A, but for T2D (BMIadjusted) GWAS versus LINC-PINT cis-eQTL. (C) Same as A, but for HDL GWAS versus LINC-PINT cis-eQTL. (D) Same as A, but for Triglycerides GWAS versus LINC-PINT cis-eQTL. (E) Same as A, but for LINC-PINT cis-eQTL versus LINC-PINT cis-aQTL. (F) Same as A, but for BMI GWAS versus AC016831.7 cis-eQTL. (G) Same as A, but for T2D (BMI-adjusted) GWAS versus AC016831.7 cis-eQTL. (H) Same as A, but for HDL GWAS versus AC016831.7 cis-eQTL. (I) Same as A, but for Triglycerides GWAS versus AC016831.7 cis-eQTL.

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