pone.0279388.s001.doc (84.5 kB)
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posted on 2023-01-04, 18:24 authored by Zubing Mei, Zhijun Zhang, Ye Han, Peixin Du, Wei Yang, Qingming Wang, De Zheng(DOC)
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subgroup analysis stratifiedrandomized controlled trialsparks 8217newcastle 8211improve patient carefunnel plot symmetricalegger 8217potential publication biascommon perianal diseasescryptoglandular anal fistulaanal fistula needprovide anorectal surgeonshigh level evidencetrue clinical effectivenesssurgical laser therapyobservational studies examininganalysis panal fistulaanorectal surgeonsclinical effectivenesslaser therapyperianal abscessobservational studiescomplex fistulabias assessmentlaser typelaser techniqueclinical outcomesyield updatedxlink ">systemic reviewsystematic reviewsearch pubmedrelevant interventionalqualitative evidencepooled estimatesperformed independentlypast decadeottawa scalenumerous studiesnatural evolutionlaird randomeligible studiesdifferent formsdata extractioncritical appraisalcomprehensive evidencecochrane librarycochrane handbookbaseline characteristicsbased recommendations36adw
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