pcbi.1011586.s003.docx (21.14 kB)
PDB depositions and chains classified by ECOD in 2016(v45) and 2022(v285).
journal contribution
posted on 2024-02-28, 18:35 authored by R. Dustin Schaeffer, Jing Zhang, Kirill E. Medvedev, Lisa N. Kinch, Qian Cong, Nick V. GrishinThe methods with the most sizeable increase between 2016 and 2022 were X-ray crystallography and electron microscopy. Electron microscopy structures commonly have many proteins (chains) as reflected in this data.
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whole proteome setscale domain annotationprotein target selection808 proteins comprisedprovide positive classificationfuture classification strategiesstable ecod referencehighly populated domains48 whole proteomesecod domain classificationdomain regionsrepeated proteinsprotein domainsevolutionary classificationvarying populationsunassigned domainstim barrelssmall repeatsrossmann domainsloop domainsidentifiable nonhomologous groupshigher proportionhigher fractionexperimental structuresdisordered regionsclassified 746biological insightsalphafold database349 domains
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