pntd.0011639.s001.docx (541.27 kB)
Nucleotide sequence (cDNA) of the additional transcriptional unit encoding the RABV-G open reading frame (orf) of rNDV_GRABV.
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posted on 2024-02-26, 18:42 authored by Magdalena Murr, Conrad Freuling, David Pérez-Bravo, Christian Grund, Thomas C. Mettenleiter, Angela Römer-Oberdörfer, Thomas Müller, Stefan FinkeDouble underlined sequences present the NDV F gene end sequence at the 5’ end or the NDV HN gene start sequence at the 3’ end, respectively. Italic sequences present the intergenic regions, separating the genes from another. Dotted underlined sequences present the 5’ and 3’ non-coding regions (including the gene start and end sequences), that are derived from the NDV HN gene. The single underlined sequence presents the orf of SAD L16 glycoprotein.
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sup >< bstrain clone 30pharyngeal lymph nodesreach spillover speciescarnivore species susceptibleviral rna couldsub >< bvirus neutralizing antibodieswildlife reservoir speciesdirect oral applicationinfectious ndv coulddiv >< psingle oral applicationempty viral vectorthree animals receivedreservoir speciesviral sheddingvaccinated animalssingle dosevirus replicationoral vaccinesoral immunizationtransgene expressiontest immunogenicitysub xmlnssimilar doseseven daysrndv ).representing herbivorenovel potentnasal swabsmammalian cellskey componentimmune responseglobal fightcell activity
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