posted on 2023-11-14, 14:16authored byTeng Long, Ya-Li Zeng, Zhi-Hong Dong, Shu Li, Jie Zhan, Sheng-Min Zeng, Jia-Li Qiu, Wen-Dao Chu, Quan-Zhong Liu
A nickel-catalyzed
three-component alkylarylation of alkenyl N-heteroarenes
with α-bromocarboxylates and aryl boronic
acids is reported. The protocol provides a new method to access a
variety of N-heteroarene substituted diarylalkanes
in moderate to good yields. It features mild reaction conditions,
cheap nickel catalyst, readily available substrates, and broad substrate
scope.