figshare
Browse
pone.0289198.s006.docx (28.62 kB)

Mutation distribution among samples passaged with or without antibody selection pressure.

Download (28.62 kB)
journal contribution
posted on 2024-01-25, 18:24 authored by Aram Avila-Herrera, Jeffrey A. Kimbrel, Jose Manuel Martí, James Thissen, Edwin A. Saada, Tracy Weisenberger, Kathryn T. Arrildt, Brent W. Segelke, Jonathan E. Allen, Adam Zemla, Monica K. Borucki

Mutation distribution among samples passaged with or without antibody selection pressure.

History

Usage metrics

    PLOS ONE

    Categories

    Keywords

    multiple mutations associateddeep sequencing revealedviral population presentviral inoculum derivedviral phenotype assaysfour times concurrentlyescaping monoclonal antibodydifferential laboratory passagingcirculating viral genotypesthree cell linespseudotyped virus stocksbiologically relevant outcomesmab assessment assaysantibody neutralization assayslaboratory viruscirculating virusviral stockphenotypic assaysstocks couldsix timesbiologically relevantantibody potencyantibody escapevitro assessmentunpassaged stockthree mabssequence diversityselective pressurerapid acquisitionoften testednatural infectionsnatural environmentmab efficacyhigh degreegenetically diversegenetic diversitydata indicateaccurately represent

    Licence

    CC BY 4.0

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC