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Mucin (Qniumucin), a Glycoprotein from Jellyfish, and Determination of Its Main Chain Structure

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journal contribution
posted on 2020-04-02, 17:31 authored by Akiko Masuda, Takayuki Baba, Naoshi Dohmae, Masahiro Yamamura, Hiroo Wada, Kiminori Ushida
We extracted a novel glycoprotein, a member of the mucin family, from five species of jellyfish with high yields (1%−3% dry weight, 0.02%−0.1% wet weight) and determined its main chain structure and molecular mass. The glycoprotein contains unique tandem repeats of eight amino acids, of which two threonine residues are probably glycosylated by N-acetyl-d-galactosamine (GalNAc). We named this substance, which is common in jellyfish and similar to the human mucin MUC5AC, “qniumucin” and suggested the utilization of this compound as a new marine resource.