pgen.1009077.s004.pdf (126.72 kB)
Methodological description of the GWAS analysis of lab traits using a summary statistic based on Area Under the Curve (AUC).
journal contribution
posted on 2020-11-11, 18:45 authored by Jeffery A. Goldstein, Joshua S. Weinstock, Lisa A. Bastarache, Daniel B. Larach, Lars G. Fritsche, Ellen M. Schmidt, Chad M. Brummett, Sachin Kheterpal, Goncalo R. Abecasis, Joshua C. Denny, Matthew Zawistowski(PDF)
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Michigan Genomics Initiative31 novel associationsdiagnosis dataGWAS associationscoding schemeBioVU samplesEHR-based measurementsfuture studiesgenome-wide significanceassociation testsVanderbilt University Health Systemlaboratory test resultsmeta-analyzed 70 lab traitsElectronic Health RecordsMGIBioVU cohortNovel findingssummary statisticshealth databiobanks PhenotypesEHR lab traitslaboratory-derived phenotypescross-health system genome-wide ass...study design recommendationshealth system GWASSuch lab dataMichigan Medicinesummary valuenovel associationslab measurementslab-based traits
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