MSP1 BloodGen3 App - Screencast 3

This short video demonstrates a functionality of the pregnancy BloodGen3 application, that is accessible via this link: https://immunology-research.shinyapps.io/BloodGen3_Pregnancy/# 

The “modules X studies” tab provides users access to fingerprint heatmap plots, for each of the aggregates and across the MSP and PROMISSE study groups. The position of the modules on the heatmap is not fixed. They are arranged instead according to similarities in abundance patterns via hierarchical clustering. In this case columns on the heatmap correspond to study groups, and rows correspond to individual modules. The proportion of transcripts for which abundance is significantly changed is shown again using gradated red and blue dots. Such maps can be accessed for each aggregate via the drop-down list directly above the plot (“Choose aggregate”). Notably, for figure preparation the zoom in/out function of the web browser can be used to increase the size of the image, thus improving its resolution. The image can then for instance be saved for used in reports or manuscript preparation.