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MALDI-TOF analysis of leachates from SOL3D PDMS devices.

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posted on 2024-03-13, 17:40 authored by Cathleen Hagemann, Matthew C. D. Bailey, Eugenia Carraro, Ksenia S. Stankevich, Valentina Maria Lionello, Noreen Khokhar, Pacharaporn Suklai, Carmen Moreno-Gonzalez, Kelly O’Toole, George Konstantinou, Christina L. Dix, Sudeep Joshi, Eleonora Giagnorio, Mads S. Bergholt, Christopher D. Spicer, Albane Imbert, Francesco Saverio Tedesco, Andrea Serio

Spectra of samples taken after incubating PDMS devices fabricated in SOL3D moulds in water at 37°C for 72 h, to mimic the conditions of the biological experiments, compared to a control consisting of water maintained at 37°C for 72 h within the same incubator and the technical control for the analysis employing only MALDI matrix. The comparison shows no detectable leachates in water incubated with the SOL3D PDMS devices, with a profile essentially comparable to what observed in the water only control.

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