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List of all strains used and generated in this study.
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posted on 2023-12-22, 18:45 authored by Jens Verbeeren, Joana Teixeira, Susana M. D. A. GarciaList of all strains used and generated in this study.
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various animal tissuesnetworks causes diseaseincurable multisystemic disordersgene shifts productiondiv >< pconserved feedback loopcentral nervous systemlifespan analyses indicatedregulate rna metabolismcaenorhabditis elegans study provides supportmbnl affects musclehighly conserved sethealthy neuromuscular functionalternative splicing reportercytoplasmic rna metabolismlong protein isoforms1 protein isoformslike protein mblalternative splicing1 protein1 isoforms1 normal lifespanlong mblcytoplasmic functionalitiesshort isoformsrespective isoformsmbnl specific crisprshort mblregulatory principlesprovide insightorganismal contextmyotonic dystrophymyotonic dystrophiesmbnl proteinskey rolegenerated strainsfunctional insufficiencyevolutionary conservationdysregulation withindm ),crucial regulatorsbiological significancebinding proteinsautoregulatory mechanism
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