posted on 2022-01-10, 18:23authored byKai Huang, Catherine Wang, Christen Vagts, Vanitha Raguveer, Patricia W. Finn, David L. Perkins
Patient information from the BAL and PBMC cohorts used in this analysis. Patients who were intubated or had PaO2/FiO2 ≤ 300 mmHg were classified as severe. In BAL, patient “Mild 3” had only 369 cells recovered after filtering and was only used for initial clustering. Exact ages were not available in the PBMC cohort. The first patient in this cohort was sampled twice, once while classified as a mild patient, and once after their symptoms worsened and required mechanical ventilation. Several patients in the PBMC cohort received azithromycin, which can have immunomodulatory effects before sample collection.