Iron-Catalyzed Thiolation
and Selenylation of Cycloalkyl
Hydroperoxides via C–C Bond Cleavage

Sun, Qing-Xin; Chen, He; Liu, Shuai; Wang, Xiao-Qiang; Duan, Xin-Hua; Guo, Li-Na

doi:10.1021/acs.joc.1c01366.s001

jo1c01366_si_001.pdf (5.57 MB)

Iron-Catalyzed Thiolation and Selenylation of Cycloalkyl Hydroperoxides via C–C Bond Cleavage

journal contribution

posted on 2021-08-10, 11:35 authored by Qing-Xin Sun, He Chen, Shuai Liu, Xiao-Qiang Wang, Xin-Hua Duan, Li-Na Guo

A cheap iron-catalyzed C–C bond cleavage/thiolation and selenylation of cycloalkyl hydroperoxides are presented. This redox-neutral protocol provides efficient access to diverse distal keto-functionalized thioethers and selenium compounds. Remarkably, only some amounts of disulfides are required for this transformation.