Iodine-Mediated δ‑Amination of sp³ C–H Bonds

We present a direct δ-amination reaction of sp³ C–H bonds, employing molecular iodine (I₂) as the sole oxidant under transition-metal-free conditions. This remote C–H functionalization approach is operationally simple and provides facile, efficient access to pyrrolidines and related heterocyclic derivatives from readily accessible substrates.