pone.0250340.s003.pdf (30.36 kB)
Histological severity of EAE in PLP TCR Tg. CD11c-DTA SJL mice.
journal contribution
posted on 2021-04-23, 17:35 authored by Thaiphi Luu, Julie F. Cheung, Jennifer Baccon, Hanspeter WaldnerHistological severity of EAE in diseased (EAE score ≥ 3) PLP TCR Tg. CD11c-DTA and PLP TCR Tg. DTA control mice (n = 3, each) as determined by quantitation of inflammatory foci in the CNS (mean number ± SEM). * p > 0.05 (Student’s t test).
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self-reactive CD 4PLP-specific CD 4myelin-specific T cellsCD 11cExperimental Autoimmune Encephalomy...TCRmyelin proteolipid proteinMSPLP T cell receptorpro-inflammatory T cell responsesSJL mice constitutivelyPLP-specific T cellsCNS myelin antigensself-reactive T cellsDCEAET cell responsesT cellsInflammatory CD 4dendritic cells results
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