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Histogram showing the most common intersects between sample-types for all differentially methylated positions.

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journal contribution
posted on 2021-03-19, 17:35 authored by Eilis Hannon, Georgina Mansell, Emma Walker, Marta F. Nabais, Joe Burrage, Agnieszka Kepa, Janis Best-Lane, Anna Rose, Suzanne Heck, Terrie E. Moffitt, Avshalom Caspi, Louise Arseneault, Jonathan Mill

Considering all sites identified as having a significantly different level of DNA methylation in at least sample type compared to whole blood (n = 611,070; ANOVA P < 9x10-8) we considered t-statistics to identify the specific sample types characterized by differential DNA methylation. Shown are the combinations of sample types with the most shared DMPs, with the vertical histogram at the top indicating the number of shared DMPs and the matrix underneath highlighting specific combinations of sample type. The colored bars in the horizontal histogram in the bottom left indicate the total number of DMPs for each sample type.

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