Higher dimensional detailed retinal phenotyping.

Currant, Hannah; Hysi, Pirro; Fitzgerald, Tomas W.; Gharahkhani, Puya; Bonnemaijer, Pieter W. M.; Senabouth, Anne; Hewitt, Alex W.; Atan, Denize; Aung, Tin; Charng, Jason; Choquet, Hélène; Craig, Jamie; Khaw, Peng T.; Klaver, Caroline C. W.; Kubo, Michiaki; Ong, Jue-Sheng; Pasquale, Louis R.; Reisman, Charles A.; Daniszewski, Maciej; Powell, Joseph E.; Pébay, Alice; Simcoe, Mark J.; Thiadens, Alberta A. H. J.; van Duijn, Cornelia M.; Yazar, Seyhan; Jorgenson, Eric; MacGregor, Stuart; Hammond, Chris J.; Mackey, David A.; Wiggs, Janey L.; Foster, Paul J.; Patel, Praveen J.; Birney, Ewan; Khawaja, Anthony P.

doi:10.1371/journal.pgen.1009497.s012

pgen.1009497.s012.pdf (83.41 kB)

Higher dimensional detailed retinal phenotyping.

journal contribution

posted on 2021-05-12, 17:47 authored by Hannah Currant, Pirro Hysi, Tomas W. Fitzgerald, Puya Gharahkhani, Pieter W. M. Bonnemaijer, Anne Senabouth, Alex W. Hewitt, Denize Atan, Tin Aung, Jason Charng, Hélène Choquet, Jamie Craig, Peng T. Khaw, Caroline C. W. Klaver, Michiaki Kubo, Jue-Sheng Ong, Louis R. Pasquale, Charles A. Reisman, Maciej Daniszewski, Joseph E. Powell, Alice Pébay, Mark J. Simcoe, Alberta A. H. J. Thiadens, Cornelia M. van Duijn, Seyhan Yazar, Eric Jorgenson, Stuart MacGregor, Chris J. Hammond, David A. Mackey, Janey L. Wiggs, Paul J. Foster, Praveen J. Patel, Ewan Birney, Anthony P. Khawaja

Mean cross-sectional models of overall retinal thickness across three groups defined by their allele state, homozygous reference, heterozygous or homozygous alternative at: (A) IGFBP3 (rs11762530), the variant with the lowest P-value aside from TSPAN10, as a control (B) TYR (rs1042602) (C) OCA2 (rs1800407) (D) TSPAN10 (rs7503894). The y axis is representative of total retinal thickness.

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