posted on 2021-09-13, 12:36authored byPavel
M. Talianov, Oleksii O. Peltek, Mikhail Masharin, Soslan Khubezhov, Mikhail A. Baranov, Audrius Drabavičius, Alexander S. Timin, Lev E. Zelenkov, Anatoly P. Pushkarev, Sergey V. Makarov, Mikhail V. Zyuzin
Halide
perovskite nanomaterials are widely used in optoelectronics
and photonics due to their outstanding luminescent properties, whereas
their strong multiphoton absorption makes them prospective for bioimaging.
Nonetheless, instability of perovskites in aqueous solutions is an
important limitation that prevents their application in biology and
medicine. Here, we demonstrate fluorescence and upconversion imaging
in living cells by employing CsPbBr3 nanocrystals (NCs)
that show an improved water-resistance (at least for 24 h) after their
coating as individual particles with various silica-based shells.
The obtained phTEOS-TMOS@CsPbBr3 NCs possess high quality,
which we confirm with high-resolution transmission and scanning transmission
electron microscopy, X-ray diffraction analysis, Fourier-transform
infrared and energy-dispersive X-ray spectroscopies, as well as with
fluorescence optical microscopy. The developed platform can make the
halide perovskite NCs suitable for various bioimaging applications.