pgen.1010882.s001.pdf (1.16 MB)
Growth and cell morphology after extended incubation in P-limited media.
journal contribution
posted on 2023-11-27, 19:11 authored by Joel Hallgren, Kira Koonce, Michele Felletti, Julien Mortier, Eloisa Turco, Kristina Jonas(A) Growth curves of wild-type cells in nutrient-replete M2G medium (black), and media limited for C (gray), N (blue), or P (orange). (B) Micrographs of cells in nutrient-replete M2G medium or after incubation in M5G 1 μM phosphate for the indicated amount of time. Scale bars: 5 μm.
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upon nutrient depletionstarved swarmer cellsstarved stalked cellssessile stalked cellsmotile swarmer stagemotile swarmer cellsdna replication initiationdna replication controldevelopmental program eithercommon mechanism involvingbacteria stop proliferatingsessile stalked cellreplication initiator dnaamotile swarmer celllimited dnaa availabilityarrest cell developmentthree starvation conditionsdistinct starvation conditionscertain starvation conditionsdecouples cell differentiationdiv >< pc ), nitrogencaulobacter crescentus starvation conditionscell differentiationcrescentus dnaa translationcell cyclec n starvationundergo physiologicalsignaling moleculesprevents ppoorly understoodmorphological changesmain reasonfindings demonstratedimorphic bacteriumdata suggestconsequently absencecellular responses
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