ppat.1011805.s004.docx (20.17 kB)
Genes upregulated by vaccination but not by infection in vaccine-matching WA1/2020 infected animals.
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posted on 2024-01-10, 18:34 authored by Juan García-Bernalt Diego, Gagandeep Singh, Sonia Jangra, Kim Handrejk, Manon Laporte, Lauren A. Chang, Sara S. El Zahed, Lars Pache, Max W. Chang, Prajakta Warang, Sadaf Aslam, Ignacio Mena, Brett T. Webb, Christopher Benner, Adolfo García-Sastre, Michael SchotsaertGenes upregulated by vaccination but not by infection in vaccine-matching WA1/2020 infected animals.
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hybrid immunity resultedbroadly reactive bvaccination reduced morbidityallowed breakthrough infectionsbreakthrough infectionsreactive seravaccination statusvaccination primedvaccinated hamsterstranscriptomics postneutralizing antibodiesinterstitial macrophageshigh titersdisease coursechallenged hamsterscell responsesancestral virusancestral spike
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