pone.0294045.s005.docx (16.29 kB)
Full associations between each candidate SNP and each of the 3 phenotypic definitions for atypical depression.
journal contribution
posted on 2023-11-15, 18:25 authored by Win Lee Edwin Wong, Ryan Arathimos, Cathryn M. Lewis, Allan H. Young, Gavin S. DaweRegression models were adjusted for age, age2, sex, genotyping batch, testing centre, and the first six European ancestry principal components. Unadjusted p values and q-values (calculated by applying false discovery rate correction across phenotype definitions) are presented.
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subsample sizes rangingmultiple testing burdenfirm biological hypothesesfindings corroborate conclusionscandidate gene studycandidate gene approacheshuman studies investigatingdiv >< pcandidate snpuk biobanksilico signalling systemrxfp3 systemprevious literatureneuropsychiatric disordersneuropeptidergic systemmetabolic syndromemetabolic phenotypeslike behaviourincluding depressiongenetic researchfollowing correctionsexploratory variablesdetermined usingatypical depressionanimal literature769 participants
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