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Fas activation pathways in the lungs.

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posted on 2021-06-17, 17:30 authored by Osamu Kajikawa, Raquel Herrero, Yu-Hua Chow, Chi F. Hung, Gustavo Matute-Bello

In alveolar epithelial cells, Fas activation can lead to apoptosis, but also to cytokine release via adapter proteins such as MyD88.

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    alveolar epithelial cellsacidintratracheal Escherichia coli lipo...Fas ligandFas-sensitive Jurkat T-cell lineT-cell line Jurkatregiontype protein functionmut-sFasL attenuated WT-sFasL functionresponse 24 hoursmice 24 hoursbioactivitycaspase -3 activityairway epithelial cellslipopolysaccharide-induced lung injury

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