Expression of NR2F2 and NR2F2-AS1 during development.

The rs372754794 SNP at the NR2F2/NR2F2-AS1 locus lies in a putative regulatory region. (A) Expression of NR2F2 and NR2F2-AS1 in human fetal retinas, analyzed from [16]. Original data sets are in S3 Data. (B) Expression of NR2F2 and NR2F2-AS1 in human retinal organoids, analyzed from [15]. Original data sets are in S6 Data. (C) ReMap ChIP-seq database [52] shows that the rs372754794 SNP lies in an enhancer based on transcription factor binding. Each colored line indicates ChIP-seq binding data for a different transcriptional regulator. The ReMap density shows the density of the peaks overlap. (D) GeneHancer database [53] shows that the rs372754794 SNP neighbors a region predicted to physically interact and regulate NR2F2 and/or NR2F2-AS1.

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